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G6PD Deficiency Association

 

Drugs that should be avoided

- Official List

Name Molecular Formula Risk Level 
(note)
For Whom Notes
 
    Low All  
    Low Medit., Asian  
Acetanilide (acetanilid) C8 H9 N O High Medit., Asian  
Acetylphenylhydrazine (2-Phynylacetohydrazide) C8 H10 N2 O High All Note
Aldesulfone sodium (sulfoxone) C14 H14 N2 Na2O6 S3 High All  
Aminophenazone (aminopyrine) C13 H17 N3 O Low All  
Antazoline (antistine) C17 H19 N3 Low All  
Arginine (acido 2(S)-ammino-5-guanidilpentanoico) C6H14N4O2 Low All  
Arsine As-H3 High All Note
Ascorbic Acid C6 H8 O6 Low All  
Beta-Naphthol (2-Naphthol) C10 H8 O High All  
Brinzolamide   High All Note
Chloramphenicol C11 H12 C12 N2 O5 High Medit., Asian  
Chloroquine C18 H26 Cl N3 High Medit., Asian Note
Ciprofloxacin C17 H18 F N3 O3 High Medit., Asian Note
Colchicine C22 H25 N O6 Low All  
Dapsone (diaphenylsulfone) C12 H12 N2 O2 S High All Note
Dimercaprol C3 H8 O S2 High All  
Diphenhydramine (difenilhydramine) C17 H21 N O Low All  
Dopamine (L-dopa) C8 H11 N O2 Low All  
Dorzolamide   High All Note
Doxorubicin C27 H29 N O11 High Medit., Asian  
Furazolidone C8 H7 N3 O5 High All  
Glibenclamide C32 H28 Cl N3 O5 S High Medit., Asian Note
Glucosulfone (glucosulfone sodium) C24 H34 N2 Na2O18 S3 High All  
Isobutyl Nitrite C4 H9 N O2 High Medit., Asian  
Isoniazid C6 H7 N3 O Low All  
Levofloxacin C18H20FN3O4 High Medit., Asian  
Menadiol Sodium Sulfate (Vitamin k4 sodium sulfate) C11 H8 Na2 O8 S2 High All Note
Menadione (menaphtone) C11 H8 O2 High All Note
Menadione sodium Bisulfite (Vitamin K3 sodium bisulfite) C11 H8 O2 NaHSO3 High All Note
Mepacrine (Quinacrine) C23 H3O Cl N3 O High Medit., Asian  
Mesalazine - 5-Aminosalicylic Acid (paraminosalicylic acid) C7 H7 N O3 High Medit., Asian  
metamizole C13H16N3NaO4S High Medit., Asian  
Methyltioninium Chloride (methylene blue) C16 H18 Cl N3 S High All  
Moxifloxacin   High Medit., Asian  
Nalidixic Acid C12 H12 N2 O3 High Medit., Asian Note
Naphtalene, Pure (naphtalin) C10 H8 High All  
Niridazole C6 H6 N4 O3 S High All  
Nitrofural (nitrofurazone) C6 H6 N4 O4 High All  
Nitrofurantoin C8 H6 N4 O5 High All  
Norfloxacin C16 H18 F N3 O3 Low All  
O-Acetylsalicylic Acid (acetylsalicylic acid) C9 H8 O4 High Medit., Asian Note
Ofloxacin   High Medit., Asian  
Oxidase, Urate (urate oxidase)   High Medit., Asian  
Pamaquine C42 H45 N3 O7 High All  
Para-Aminobenzoic Acid (4-Aminobenzoic Acid) C7 H7 N O2 Low All  
Paracetamol (acetaminophen) C8 H9 N O2 Low All  
Pentaquine C18 H27 N3 O High All  
Phenacetin (acetophenetidin) C10 H13 N O2 High Medit., Asian

 

Phenazone (antipyrine) C11 H12 N2 O Low All  
Phenazopyridine C11 H11 N5 High Medit., Asian  
Phenylbutazone C19 H20 N2 O2 Low All  
Phenytoin C19 H20 N2 O2 Low All  
Phynylhydrazine C6 H8 N2 High All Note
Phytomenadione (Vitamin K1) C31 H46 O2 Low All  
Primaquine C15 H21 N3 O High All Note
Probenecid C13 H19 NO4 S High All  
Procainamide C13 H21 N3 O Low All  
Proguanil (chlorguanidine) C11 H16 Cl N5 Low All  
Pyrimethamine C12 H13 Cl N4 Low All  
Quinidine C20 H24 N2 O2 Low All  
Quinine C20 H24 N2 O2 Low All  
Rasburicase   High Medit., Asian  
Stibophen (2-(2-Oxido-3,5-Disulphonatophenoxy)-1,3,2,Benzodioxastibole-4-6-Disulphonate) C12 H4 Na5 O16 S4Sb High All  
Streptomycin C21 H39 N7 O12 Low All  
Sulfacetamide C8 H10 N2 O3 S High All  
Sulfacytine C12 H14 N4 O3 S Low All  
Sulfadiazine C10 H10 N4 O2 S Low All  
Sulfadimidine C12 H14 N4 O2 S High All  
Sulfafurazole (sulfafurazone, sulfisoxazole) C11 H13 N3 O3 S High Medit., Asian  
Sulfaguanidine C7 H10 N4 O2 S Low All  
Sulfamerazine C11 H12 N4 O2 S Low All  
Sulfamethoxazole C10 H11 N3 O3 S High All Note
Sulfamethoxypyridazine C11 H12 N4 O3 S Low All  
Sulfanilamide (Sulphanilamide) C6 H8 N2 O2 S High All  
Sulfapyridine C11 H11 N3 O2 S High All  
Sulfasalazine, Salazosulfapyridine (salazopyrin) C18 H14 N4 O5 S High All  
Thiazosulfone (thiazolesulfone) C9 H9 N3 O2 S2 High Medit., Asian  
Tiaprofenic Acid C14 H12 O3 S Low All  
Tolonium Chloride, Tolonium Chloride (toluidine blue) C15 H16 Cl N3 S High All  
Trihexyphynidyl (benzhexol) C20 H31 N O Low All  
Trimethoprim C14 H18 N4 O3 Low All Note
Trinitrotoluene (2,4,6-Trinitrotoluene) C7 H5 N3 O6 High Medit., Asian  
Tripelennamine C16 H21 N3 Low Medit., Asian

以上資料來源http://www.g6pd.org

 

 

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